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TSC2
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Related Signaling Pathways
Insulin Signaling Pathway
mTOR Signaling Pathway
PI3K-Akt Signaling Pathway
Related Diseases
Insulin Resistance
- Rabbit Anti-TSC2 Recombinant Antibody (clone CBACN-564) (MRO-1538-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, FC
- Rabbit Anti-TSC2 Polyclonal Antibody (MRO-2245-CN) (MRO-2245-CN)
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: IF, IHC, FC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IF, IHC-P, WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, IP-MS
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC, FC
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For Research Use Only. Not For Clinical Use.