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VCAM1

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
VCAM1
Protein class

Cancer-related genes, CD markers, Plasma proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Kupffer cells, Proximal tubular cells, Theca cells, Ductal cells, Hepatic stellate cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (HHSteC, HSkMC)

More Types Infomation

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