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VTCN1

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Ductal cells, Glandular and luminal cells, Breast glandular cells, Collecting duct cells, Endometrial ciliated cells, Exocrine glandular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SK-BR-3)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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