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ACAD8
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.
Protein class
Disease related genes, Human disease related genes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homotetramer, formed by a dimer of dimers (PubMed:11013134, PubMed:14752098). May be part of the large multiprotein complex ARC/DRIP (PubMed:10235267).
Molecular function
Activator, Oxidoreductase
More Types Infomation
- Chicken Anti-ACAD-8 (ab2) Polyclonal IgY (BRD-0011MZ)
-
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
- Chicken Anti-ACAD-8 (ab1) Polyclonal IgY (BRD-0010MZ)
-
- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.