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AIFM2
This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells. [provided by RefSeq, Nov 2010]
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (Hep G2)
Interaction
Interacts with importin subunits KPNA2 and IPO5; this interaction likely mediates the translocation into the nucleus upon oxidative stress.
Molecular function
DNA-binding, Oxidoreductase
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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- Species Reactivity: Human, Mouse, Rat, Monkey, Hamster
- Type: Mouse IgG2b
- Application: IP, FC, IF
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- Species Reactivity: Human, Monkey, Mouse, Rat
- Type: Mouse IgG2b
- Application: ELISA, WB, IP, IHC
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For Research Use Only. Not For Clinical Use.