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AKAP1

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Group enriched (Late spermatids, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with SLC8A3 (By similarity). Interacts with CFAP91 (PubMed:12223483). Interacts with CLPB (PubMed:31522117). Interacts with NDUFS1 (By similarity).

Molecular function

RNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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