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AKAP3

This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction.
Predicted location

Intracellular

Single cell type specificity

Group enriched (Early spermatids, Late spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (JURKAT, NTERA-2)

Interaction

Interacts with ROPN1 AND ROPN1L. Interacts with QRICH2 (PubMed:30683861).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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