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APBB1IP
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Microglial cells, dendritic cells, NK-cells, T-cells, Kupffer cells, Macrophages, B-cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (Daudi, MOLT-4, REH, U-698)
Interaction
Interacts, through the N-terminal Pro-rich region, with the WW domain of APBB1. Interacts with RAP1A, PFN1, TLN1, VASP, VCL and ENAH.
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IHC-P, IP, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC, IHC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, FC
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For Research Use Only. Not For Clinical Use.