Loading...
Custom Services order now ship next day

ATF3

This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Basal squamous epithelial cells, Glandular and luminal cells, Endometrial ciliated cells)

Immune cell specificity

Group enriched (basophil, non-classical monocyte, intermediate monocyte, myeloid DC)

Cell line specificity

Cell line enhanced (BEWO, HDLM-2, SuSa)

Interaction

Binds DNA as a homodimer or a heterodimer. Interacts with KAT5; promoting KAT5 autoacetylation and KAT5 deubiquitination by USP7 (PubMed:25865756).

Molecular function

DNA-binding, Repressor

More Types Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

For Research Use Only. Not For Clinical Use.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare