Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets
Intracellular, Membrane (different isoforms)
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with STUB1/CHIP (when monoubiquitinated) (By similarity). Interacts with DNA repair proteins RAD23A and RAD23B (PubMed:16020535, PubMed:30455355). Interacts with BECN1 (via its poly-Gln domain) (PubMed:28445460). Interacts with PRKN, UBR2, VCP and tubulin. Short isoform 1 interacts with CASP7 (PubMed:30455355).
Hydrolase, Protease, Thiol protease
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For Research Use Only. Not For Clinical Use.