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BSG
Predicted to enable cell-cell adhesion mediator activity; signaling receptor activity; and virus receptor activity. Involved in neural retina development; photoreceptor cell maintenance; and spermatogenesis. Located in several cellular components, including acrosomal membrane; photoreceptor inner segment; and photoreceptor outer segment. Is expressed in several structures, including alimentary system; brain; early conceptus; reproductive system; and sensory organ. Orthologous to human BSG (basigin (Ok blood group)).
Protein class
Blood group antigen proteins, CD markers, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
[Isoform 1]: Homooligomer (PubMed:19768682). Interacts with NXNL1 (PubMed:25957687). Interacts with SLC2A1 and SLC16A1/GLUT1 (By similarity). Interacts with XKR8; promoting its localization at the cell membrane (PubMed:27503893). [Isoform 2]: Homooligomer (PubMed:18430721). Forms heterooligomers with isoform 3 (PubMed:21536654). Interacts with VEGFA and KDR/VEGFR2 (PubMed:25825981). Interacts with PPIA/CYPA (PubMed:11353871, PubMed:11943775, PubMed:15688292, PubMed:21245143). Interacts with PPIL2; regulates BSG transport to the cell membrane (PubMed:15946952). Interacts with SLC16A1/GLUT1 (PubMed:17127621). Interacts with SLC16A12 (PubMed:21778275). Interacts with SLC16A11 (PubMed:28666119). Interacts with AJAP1 (PubMed:17267690). Interacts with SLC1A3, ATP1B2, MAG and L1CAM (By similarity). [Isoform 3]: Forms heterooligomers with isoform 2. [Isoform 1]: (Microbial infection) Interacts with P.falciparum (isolate 3D7) RH5/PfRH5; the interaction is required for the invasion of the host erythrocytes by the parasite at the merozoite stage. [Isoform 2]: (Microbial infection) Interacts with P.falciparum (isolates 3D7 or 7G8) RH5/PfRH5; the interaction is required for the invasion of the host erythrocytes by the parasite at the merozoite stage. [Isoform 2]: (Microbial infection) Does not interact with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, even if previous works were based on a putative interaction.
Molecular function
Blood group antigen, Host cell receptor for virus entry, Receptor
More Types Infomation
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, FuncS
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, FuncS
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG
- Application: WB, ELISA, FuncS
- Mouse Anti-BSG Recombinant Antibody (clone WK2/0) (MOB-1965MZ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB
- Mouse Anti-BSG Recombinant Antibody (clone Ab-1); Fab Fragment (FAMAB-0033CQ-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Block
- Mouse Anti-BSG Recombinant Antibody (clone 11A6) (MOB-1683z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, FC, ICC, IF
-
- Derivation: Human
- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, FuncS
- Human Anti-BSG Recombinant Antibody (clone Ab-1) (NEUT-070CQ)
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- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, Block
- Mouse Anti-BSG Recombinant Antibody (clone HIM6) (NEUT-071CQ)
-
- Species Reactivity: Human, Chimpanzee, Baboon, Capuchin Monkey
- Type: Mouse IgG1, κ
- Application: FC, WB, IHC, Block
- Mouse Anti-BSG Recombinant Antibody (clone Ab-1) (FAMAB-0033CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, Block
- Human Anti-BSG Recombinant Antibody (clone chAb-1) (FAMAB-0034CQ)
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: ELISA, Block
- Mouse Anti-BSG Recombinant Antibody (clone Ab-1); scFv Fragment (FAMAB-0033CQ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Block
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Human Anti-BSG Recombinant Antibody (clone chAb-1); Fab Fragment (FAMAB-0034CQ-F(E))
-
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: ELISA, Block
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, FC
- Rabbit Anti-BSG Polyclonal Antibody (MRO-1735-CN) (MRO-1735-CN)
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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For Research Use Only. Not For Clinical Use.