Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Oligodendrocytes, Kupffer cells, Microglial cells)
Not detected in immune cells
Cell line enhanced (MCF7, SK-BR-3, T-47d)
Interacts (via CARD domain) with BCL10 (via CARD domain) (PubMed:21302310). Forms a complex with MALT1 and BCL10; resulting in the formation of a CBM (CARD14-BLC10-MALT1) complex (PubMed:27113748, PubMed:27071417). Interacts with TRAF2, TRAF3 and TRAF6 (PubMed:21302310).
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For Research Use Only. Not For Clinical Use.