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CARM1

CARM1 (Coactivator Associated Arginine Methyltransferase 1) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and transcription regulatory region DNA binding. An important paralog of this gene is PRMT3.
Protein class

Cancer-related genes, Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Homodimer (Probable). Interacts with the C-terminus of NCOA2/GRIP1, NCO3/ACTR and NCOA1/SRC1. Part of a complex consisting of CARM1, EP300/P300 and NCOA2/GRIP1. Interacts with FLII, TP53, myogenic factor MEF2, EP300/P300, TRIM24, CREBBP and CTNNB1. Identified in a complex containing CARM1, TRIM24 and NCOA2/GRIP1. Interacts with NCOA3/SRC3. Interacts with SNRPC (By similarity). Interacts with NR1H4. Interacts with RELA. Interacts with SKP2 (By similarity). Interacts (via PH domain-like fold) with C9orf72 (By similarity). (Microbial infection) Interacts with HTLV-1 protein Tax.

Molecular function

Chromatin regulator, Methyltransferase, Transferase

More Types Infomation

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