Disease related genes, Human disease related genes, Potential drug targets, Transporters
Membrane
Cell type enhanced (Cardiomyocytes, Skeletal myocytes, Sertoli cells, Early spermatids)
Not detected in immune cells
Cell line enriched (RH-30)
Homooligomer. Interacts with DLG1 and KCNA5; forms a ternary complex. Interacts with TRIM72. Interacts with MUSK; may regulate MUSK signaling. Interacts with DAG1 (via its C-terminal); the interaction prevents binding of DAG1 with DMD (PubMed:10988290). Interacts with DYSF (PubMed:11532985). Interacts with BVES (By similarity). Interacts with CAVIN1 and CAVIN2 (PubMed:24567387). Interacts with CAVIN4 (PubMed:24567387, PubMed:11251997).
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For Research Use Only. Not For Clinical Use.