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CCL15

This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14).
Protein class

Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Paneth cells, Distal enterocytes, Intestinal goblet cells, Undifferentiated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (Hep G2, OE19)

Interaction

Monomer.

Molecular function

Cytokine, Heparin-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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