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CDH6

This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
Protein class

Plasma proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Proximal tubular cells, Smooth muscle cells, Excitatory neurons, Pancreatic endocrine cells, Oligodendrocyte precursor cells, Cholangiocytes, Sertoli cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (EFO-21)

More Types Infomation

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