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CH25H
This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008]
Protein class
Enzymes, Metabolic proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Basal squamous epithelial cells, Adipocytes, Smooth muscle cells, Macrophages, Microglial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Molecular function
Monooxygenase, Oxidoreductase
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.