Loading...
CHD5
This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma.
Protein class
Disease related genes, Enzymes, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Horizontal cells, Early spermatids, Late spermatids, Bipolar cells, Excitatory neurons, Inhibitory neurons, Rod photoreceptor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (SCLC-21H, U-2 OS)
Interaction
May be part of a nucleosome remodeling and histone deacetylation, NuRD-like, complex composed at least of GATAD2B, HDAC1, HDAC2 and MTA3.
Molecular function
Chromatin regulator, DNA-binding, Helicase, Hydrolase
More Types Infomation
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.