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CHL1
The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants.
Protein class
Plasma proteins
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Oligodendrocyte precursor cells, Excitatory neurons, Inhibitory neurons, Astrocytes)
Immune cell specificity
Group enriched (naive B-cell, memory B-cell)
Cell line specificity
Group enriched (SK-MEL-30, WM-115)
Interaction
May interact with L1CAM. May interact with ITGB1/ITGA1 heterodimer and ITGB1/ITGA2 heterodimer as well as with ANK3 (By similarity).
Molecular function
Developmental protein
More Types Infomation
- Rat Anti-CHL1 Recombinant Antibody (clone YC021) (MOB-038LC)
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- Species Reactivity: Human
- Type: Rat IgG
- Application: WB
- Recombinant Human Anti-human CHL1 Antibody scFv Fragment (MHH-200-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, WB, FuncS
- Recombinant Anti-human CHL1 Antibody scFv Fragment (MOB-200-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
- Human Anti-CHL1 Recombinant Antibody (clone 6C2); scFv Fragment (FAMAB-0065-YC-S(P))
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- Derivation: Phage display library
- Species Reactivity: Mouse
- Type: Human scFv
- Application: ELISA, IF, WB
- Recombinant Human Anti-human CHL1 Antibody Fab Fragment (MHH-200-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, Neut, FuncS
- Recombinant Anti-human CHL1 Antibody Fab Fragment (MOB-200-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, FuncS
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: IF, WB, FuncS
- Human Anti-CHL1 Recombinant Antibody (clone 6C2); Fab Fragment (FAMAB-0065-YC-F(E))
-
- Derivation: Phage display library
- Species Reactivity: Mouse
- Type: Human Fab
- Application: ELISA, IF, WB
- Human Anti-CHL1 Recombinant Antibody (clone 6C2) (FAMAB-0065YC)
-
- Derivation: Phage display library
- Species Reactivity: Mouse
- Type: Human IgG
- Application: ELISA, IF, WB
- Recombinant Anti-human CHL1 Antibody (MOB-200)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FuncS
- Rabbit Anti-CHL1 Polyclonal Antibody (CBPAB-045LC)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC, WB
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For Research Use Only. Not For Clinical Use.