Loading...
Custom Services order now ship next day

CHRD

This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined.
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Hepatocytes, Endometrial stromal cells, Excitatory neurons, Skeletal myocytes, Fibroblasts, Smooth muscle cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CACO-2, Hep G2, MCF7, SuSa, U-2 OS)

Interaction

Interacts with TWSG1 and/or BMP4.

Molecular function

Developmental protein

More Types Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

For Research Use Only. Not For Clinical Use.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare