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CHST3

This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Granulosa cells, Skeletal myocytes, Oligodendrocyte precursor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (U-251 MG)

Molecular function

Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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