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CHTF18
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Bipolar cells, Granulosa cells, Spermatogonia, Extravillous trophoblasts)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Cell line enhanced (BEWO)
Interaction
Component of the CTF18-RFC complex, which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5 (PubMed:12766176, PubMed:12930902). During assembly of the CTF18-RFC complex, CTF18 may first assemble into a subcomplex with RFC2, RFC3, RFC4 and RFC5. CTF18 then interacts directly with CTF8, which in turn interacts with DCC1 (PubMed:12766176, PubMed:12930902). The CTF18-RFC complex associates with PCNA and with DNA polymerase POLH (PubMed:12766176, PubMed:17545166). The CTF18-RFC complex does not interact with the Rad9/Rad1/Hus1 complex (PubMed:12766176). CTF18 interacts with SMC1A and RAD21 (PubMed:12930902). Interacts with DDX11 (PubMed:18499658).
Molecular function
DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IP, WB
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For Research Use Only. Not For Clinical Use.