Intracellular, Membrane (different isoforms)
Cell type enhanced (Kupffer cells, Macrophages, monocytes, Glandular and luminal cells)
Group enriched (neutrophil, classical monocyte)
Group enriched (NB-4, RPTEC TERT1)
Monomer and homodimer (PubMed:18509109). Interacts with signaling adapter Fc receptor gamma chain/FCER1G to form a functional complex; the interaction is direct (By similarity). Alternatively, acts as a bridge for interaction between CLEC4D and FCER1G. A heterodimer of CLEC4E and CLEC4D associates with FCER1G to form a functional complex (By similarity). Interacts with SAP130 nuclear protein that is released from necrotic cells; the interaction is direct (By similarity).
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For Research Use Only. Not For Clinical Use.