Disease related genes, Enzymes, Human disease related genes, Potential drug targets
Intracellular
Cell type enhanced (Early spermatids)
Low immune cell specificity
Low cell line specificity
Component of the tRNA splicing endonuclease complex, composed of CLP1, TSEN2, TSEN15, TSEN34 and TSEN54 (PubMed:24766809). Component of pre-mRNA cleavage complex II (CF-II). Also associates with numerous components of the pre-mRNA cleavage complex I (CF-I/CFIm), including NUDT21, CPSF2, CPSF3, CPSF6 and CPSF7. Interacts with CSTF2 and SYMPK.
Kinase, Transferase
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For Research Use Only. Not For Clinical Use.