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COX18

This gene encodes a cytochrome c oxidase assembly protein. The encoded protein is essential for integral membrane protein insertion into the mitochondrial inner membrane. It is also required for cytochrome c oxidase assembly and activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Protein class

Transporters

Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Found in a complex with TMEM177, COA6, MT-CO2/COX2, COX20, SCO1 and SCO2 (PubMed:29154948). Interacts transiently with MT-CO2/COX2 during its maturation (PubMed:28330871). Interacts with COX20 in a MT-CO2/COX2-dependent manner (PubMed:28330871).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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