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CPM
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Protein class
Enzymes, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Sertoli cells, Kupffer cells, Alveolar cells type 2, Alveolar cells type 1)
Immune cell specificity
Group enriched (classical monocyte, myeloid DC, intermediate monocyte, non-classical monocyte)
Cell line specificity
Group enriched (ASC diff, ASC TERT1, HSkMC, SiHa, THP-1)
Molecular function
Carboxypeptidase, Hydrolase, Metalloprotease, Protease
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P
- Rabbit Anti-CPM Recombinant Antibody (clone CBC253) (MOB-268YJL)
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Human
- Application: IHC-Fr, IHC-P
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IHC, IP
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For Research Use Only. Not For Clinical Use.