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CPOX

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Erythroid cells, Oligodendrocytes, Extravillous trophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HEL)

Interaction

Homodimer.

Molecular function

Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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