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CRABP2

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Squamous epithelial cells, Urothelial cells, Basal respiratory cells, Club cells, Breast glandular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BJ hTERT+, MCF7, T-47d)

Interaction

Interacts with RXR and RARA (By similarity). Interacts with importin alpha.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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