Plasma proteins
Intracellular
Group enriched (Late spermatids, Early spermatids)
Not detected in immune cells
Low cell line specificity
Part of a Cul9-RING complex at least composed of CUL9 and RBX1. Interacts with CUL7: interaction with CUL7 component of the 3M complex leads to inhibition of CUL9 activity. The CUL7-CUL9 heterodimer seems to interact specifically with TP53. Forms a complex with p53/TP53 in the cytoplasm of unstressed cells. Interacts with UBCH7 and UBCH8.
Transferase
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For Research Use Only. Not For Clinical Use.