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CXCL6

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).
Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Ductal cells, Basal respiratory cells, Club cells, Urothelial cells, Cholangiocytes, Prostatic glandular cells, Basal prostatic cells)

Immune cell specificity

Immune cell enriched (neutrophil)

Cell line specificity

Cell line enhanced (BJ hTERT+, EFO-21, hTEC/SVTERT24-B, HUVEC TERT2, RPTEC TERT1)

Molecular function

Antibiotic, Antimicrobial, Cytokine, Heparin-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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