Enzymes, Metabolic proteins, Plasma proteins
Intracellular, Membrane (different isoforms)
Cell type enhanced (Adipocytes, Urothelial cells, Endothelial cells, Hepatocytes, Glandular and luminal cells)
Not detected in immune cells
Cell line enhanced (CACO-2, hTCEpi, HUVEC TERT2, SK-BR-3, SuSa)
Interacts with cytosolic chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria. Interacts (via mitochondrial targeting signal) with TOMM40 (via N-terminus); this interaction is required for translocation across the mitochondrial outer membrane.
Lyase, Monooxygenase, Oxidoreductase
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For Research Use Only. Not For Clinical Use.