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CYP27A1

CYP27A1 (Cytochrome P450 Family 27 Subfamily A Member 1) is a Protein Coding gene. Diseases associated with CYP27A1 include Cerebrotendinous Xanthomatosis and Xanthomatosis. Among its related pathways are Metabolism and Cytochrome P450-arranged by substrate type. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP27B1.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hepatocytes, Proximal enterocytes, Hofbauer cells)

Immune cell specificity

Group enriched (classical monocyte, neutrophil)

Cell line specificity

Cell line enhanced (Hep G2, HSkMC, RPTEC TERT1, SK-MEL-30, WM-115)

Interaction

Interacts with HSP70; this interaction is required for initial targeting to mitochondria.

Molecular function

Monooxygenase, Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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