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CYP2E1
CYP2E1 (Cytochrome P450 Family 2 Subfamily E Member 1) is a Protein Coding gene. Diseases associated with CYP2E1 include Alcohol Abuse and Fatty Liver Disease. Among its related pathways are Caffeine Pathway, Pharmacokinetics and Acetaminophen Pathway (therapeutic doses), Pharmacokinetics. Gene Ontology (GO) annotations related to this gene include enzyme binding and iron ion binding. An important paralog of this gene is CYP2C9.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Hepatocytes)
Immune cell specificity
Immune cell enhanced (myeloid DC, MAIT T-cell)
Cell line specificity
Cell line enhanced (HaCaT, HL-60, HMC-1, NB-4)
Interaction
Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
Molecular function
Monooxygenase, Oxidoreductase
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB
- Rabbit Anti-CYP2E1 Recombinant Antibody (clone JM10-85) (MRO-0424-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, IF, IHC
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- Species Reactivity: Rat
- Application: WB
- Rabbit Anti-CYP2E1 Polyclonal Antibody (MRO-1803-CN) (MRO-1803-CN)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC
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For Research Use Only. Not For Clinical Use.