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DBF4
DBF4 (DBF4 Zinc Finger) is a Protein Coding gene. Among its related pathways are E2F mediated regulation of DNA replication and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and enzyme activator activity. An important paralog of this gene is DBF4B.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Spermatocytes, Early spermatids)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Low cell line specificity
Interaction
Forms a complex with CDC7. Note that CDC7 forms distinct complex either with DBF4A or DBF4B. Such complexes are stable upon replication stress. Interacts with MEN1, MCM2, ORC2, ORC4 and ORC6. Interacts (via IBM motifs) with PSIP1 (via IBD domain); phosphorylation increases its affinity for PSIP1 (PubMed:29997176).
More Types Infomation
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- Species Reactivity: Human
- Application: IHC-P, WB
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IF
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For Research Use Only. Not For Clinical Use.