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DBP

PvDBP has been divided into six distinct regions, with the DARC binding site mapped to a ~350 amino acid residue Duffy-binding-like (DBL) domain known as Region II, PvDBPII. This domain is split into three regions, known as subdomains.
Protein class

Metabolic proteins, Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Bipolar cells, Horizontal cells, Muller glia cells, Rod photoreceptor cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Karpas-707, NB-4)

Interaction

Binds DNA as a homodimer or a heterodimer. Can form a heterodimer with TEF.

Molecular function

Activator, DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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