Disease related genes, Human disease related genes
Intracellular
Cell type enhanced (Cone photoreceptor cells)
Low immune cell specificity
Low cell line specificity
Interacts with ATM, BRCA1, PRKDC and TP53BP1. Also exhibits ATM- and phosphorylation-dependent interaction with the MRN complex, composed of MRE11, RAD50, and NBN.
Endonuclease, Exonuclease, Hydrolase, Nuclease
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For Research Use Only. Not For Clinical Use.