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DCSTAMP

This is an antibody that specifically binds an epitope of DC-STAMP, it is being assessed for it's therapeutic implications in autoimmune and bone disease.
Protein class

Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Hofbauer cells, Macrophages)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (U-87 MG)

Interaction

Monomer. Homodimer. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 1 (via the C-terminus tail); the interaction induces DCSTAMP redistribution to the endoplasmic reticulum-Golgi intermediate compartment. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 2 (via the C-terminus tail) (By similarity). Interacts with CREB3.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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