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DDIT4

DDIT4 (DNA Damage Inducible Transcript 4) is a Protein Coding gene. Among its related pathways are Gene Expression and Direct p53 effectors. Gene Ontology (GO) annotations related to this gene include 14-3-3 protein binding. An important paralog of this gene is DDIT4L.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Plasma cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HBEC3-KT, hTCEpi, hTERT-HME1)

Interaction

Monomer. Interacts with BTRC. Identified in a complex with CUL4A, DDB1 and BTRC. Interacts with TXNIP; this inhibits the proteasomal degradation of DDIT4.

More Types Infomation

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