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DKK4
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2.
Predicted location
Secreted
Single cell type specificity
Group enriched (Urothelial cells, Basal prostatic cells, Pancreatic endocrine cells, Prostatic glandular cells, Spermatocytes, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (OE19)
Interaction
Interacts with LRP5 and LRP6.
Molecular function
Developmental protein
More Types Infomation
Related Signaling Pathways
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.