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DKKL1

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Group enriched (Late spermatids, Early spermatids)

Immune cell specificity

Immune cell enriched (memory B-cell)

Cell line specificity

Cell line enhanced (AF22, AN3-CA, HeLa)

Interaction

Interacts with SLXL1; Co-localize in seminiferous tubules. Interacts with SLY.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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