DLX1

DLX1 (Distal-Less Homeobox 1) is a Protein Coding gene. This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. Diseases associated with DLX1 include Split-Hand/Foot Malformation 5 and Dental Fluorosis.