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DRAM1

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Protein class

Transporters

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Alveolar cells type 2, Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enriched (BJ hTERT+)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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