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EDA2R
The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms.
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Granulosa cells, Oligodendrocytes, Microglial cells, Theca cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC TERT1, HSkMC, LHCN-M2, SuSa)
Interaction
Associates with TRAF1, TRAF3 and TRAF6.
Molecular function
Developmental protein, Receptor
More Types Infomation
- Mouse Anti-EDA2R Recombinant Antibody (clone CBL844) (NEUT-716CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Neut
- Mouse Anti-EDA2R Recombinant Antibody (clone CBL343) (NEUT-714CQ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Block, WB
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.