Plasma proteins
Secreted
Cell type enhanced (Langerhans cells, Endometrial stromal cells, Macrophages, Hofbauer cells, Kupffer cells, monocytes)
Immune cell enhanced (basophil)
Cell line enhanced (ASC diff, BEWO, HL-60, HMC-1, HSkMC, SuSa, THP-1, U-2197)
Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quaternary assembly to higher-order polymers via intermolecular disulfide bonds (By similarity). Interacts with EMILIN1.
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For Research Use Only. Not For Clinical Use.