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ENDOG
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Respiratory ciliated cells, Endometrial ciliated cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer; disulfide-linked (By similarity). Homodimerization is essential for enzyme activity (By similarity). Interacts with YWHAG (PubMed:33473107).
Molecular function
Endonuclease, Hydrolase, Nuclease
More Types Infomation
- Rabbit Anti-ENDOG Recombinant Antibody (clone JU31-30) (MRO-0533-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.