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ERF
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 [PubMed 9192842]). For further information on ETS transcription factors, see ETS1 (MIM 164720).[supplied by OMIM, Mar 2008]
Protein class
Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Basal keratinocytes, Suprabasal keratinocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Molecular function
DNA-binding, Repressor
More Types Infomation
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- Species Reactivity: Human
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.