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ERI1

ERI1 (Exoribonuclease 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and ribosome binding. An important paralog of this gene is ERI3.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Early spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Identified in a histone pre-mRNA complex, at least composed of ERI1, LSM11, SLBP, SNRPB, SYNCRIP and YBX1. Interacts in a cooperative manner with SLBP to the mature 3'-end of histone mRNAs (By similarity). Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Found in a ternary complex with SLBP and the stem-loop structure of the 3'-end of histone mRNAs.

Molecular function

Exonuclease, Hydrolase, Nuclease, RNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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