Plasma proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Forms mixed disulfides with both ERO1A and ERO1B and cargo folding intermediates. Directly interacts with ITPR1 in a pH-, redox state- and calcium-dependent manner, but not with ITPR2 or ITPR3. The strength of this interaction inversely correlates with calcium concentration (By similarity).
Chaperone
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For Research Use Only. Not For Clinical Use.