Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Intracellular
Cell type enhanced (Early spermatids, Late spermatids, Microglial cells, Oligodendrocytes, Hepatocytes)
Immune cell enriched (basophil)
Cell line enhanced (RH-30)
Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70. The complex is not found in FA patients. Interacts with ZBTB32. Upon IFNG induction, interacts with STAT1. Interacts with CDK1. Interacts with EIF2AK2; interaction between FA variants and EIF2AK2 may lead to augmented EIF2AK2 activation and cell death.
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For Research Use Only. Not For Clinical Use.