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FATE1

This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation.
Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Late spermatids, Early spermatids, Sertoli cells, Spermatocytes, Theca cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Interacts with BIK and RNF183 (PubMed:26567849). Interacts with IMMT/MIC60and EMD (PubMed:27402544).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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